- Analgetics Acetaminophen Salicylates Codeine
Godamed companies and manufacturers:
- Dr. R. Pfleger - Gramse Pharmaceuticals
Godamed forms, composition and dosages:
- Tablet; Oral; Aspirin 100 mg
Indications, usages and classification codes:
- B01AC06 - Acetylsalicylic Acid - N02BA01 - Acetylsalicylic Acid
Why is Godamed prescribed?
Rheumatism, rheumatoid arthritis, infectious-allergic myocarditis, fever during infectious and inflammatory diseases, pain syndrome, weak and medium intensity of various origins (including neuralgia, myalgia, headache); based prevention of thrombosis and embolism, primary and secondary prevention of myocardial infarction, prevention of violations of cerebral circulation by ischemic type .
Godamed side effects
Digestive system: nausea, vomiting, anorexia, epigastric pain, diarrhea; rarely - occurrence of erosive and ulcerative lesions, bleeding from the gastrointestinal tract, abnormal liver function. Central nervous system: long-term use may be dizziness, headache, reversible visual disturbances, tinnitus, aseptic meningitis. Hemopoietic system: rarely - thrombocytopenia, anemia. Blood coagulation system: rarely - haemorrhagic syndrome, prolongation of bleeding time. Urinary system: rarely - renal dysfunction, with prolonged use - acute kidney failure, nephrotic syndrome. Allergic reactions: rarely - skin rash, Quincke's edema, bronchospasm, "aspirin triad" (a combination of bronchial asthma, recurrent nasal polyposis, and paranasal sinuses and intolerance of acetylsalicylic acid and medicines pirazolonic series). Other: in some cases - Reye syndrome, long-term use - increased symptoms of chronic heart failure.
Godamed drug interactions
With simultaneous use of antacids containing magnesium and / or aluminum hydroxide, slow down and reduce the absorption of acetylsalicylic acid. With simultaneous use of calcium channel blockers, means limiting intake of calcium or increasing the excretion of calcium from the body, increases the risk of bleeding. With simultaneous use with acetylsalicylic acid enhances the action of heparin and indirect anticoagulants, hypoglycemic funds derived sulfonylureas, insulin, methotrexate, phenytoin, valproic acid. With simultaneous use of SCS increases the risk of ulcerogenic effect and occurrence of gastrointestinal bleeding. With simultaneous use of decreasing the effectiveness of diuretics (spironolactone, furosemide). With simultaneous use of other NSAIDs increases the risk of side effects. Acetylsalicylic acid may reduce plasma concentrations indomethacin, piroxicam. With simultaneous use of gold drugs acetylsalicylic acid can induce liver damage. With simultaneous use decreases effectiveness of uricosuric medications (including probenecid, sulfinpirazon, benzbromarone). With simultaneous use of acetylsalicylic acid and alendronate sodium may develop severe esophagitis. With simultaneous use of griseofulvin may be in breach Absorption of acetylsalicylic acid. There is one case of spontaneous hemorrhage in the iris while taking Ginkgo Biloba extract on the background of prolonged use of aspirin in a dose of 325 mg / day. It is believed that this may be due to additive inhibitory effect on platelet aggregation. With simultaneous use of dipyridamole may increase Cmax of salicylate in plasma and AUC. When applied simultaneously with acetylsalicylic acid increased concentration of digoxin, barbiturates and lithium salts in the blood plasma. With simultaneous use of salicylates in high doses with carbonic anhydrase inhibitors can intoxication salicylates. Acetylsalicylic acid in doses of less than 300 mg have little effect on the effectiveness of captopril and enalapril. When aspirin (acetylsalicylic acid) is admistered in high doses may decrease the effectiveness of captopril and enalapril. With simultaneous application of caffeine increases the rate of absorption, plasma concentrations and bioavailability of acetylsalicylic acid. With simultaneous use of metoprolol may increase Cmax of salicylate in blood plasma. In the application of pentazocine on the background of long-term use of aspirin in high doses there is a risk of severe adverse reactions in the kidneys. With simultaneous application phenylbutazone reduces uricosuria caused by acetylsalicylic acid. With simultaneous application of ethanol may exacerbate the effects of acetylsalicylic acid on the gastrointestinal tract.